Elacestrant dihydrochloride
CAS No. 1349723-93-8
Elacestrant dihydrochloride ( RAD-1901 dihydrochloride )
Catalog No. M11413 CAS No. 1349723-93-8
Elacestrant (RAD-1901) is a novel, orally bioavailable small-molecule selective estrogen receptor degrader (SERD).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 224 | Get Quote |
|
10MG | 356 | Get Quote |
|
25MG | 599 | Get Quote |
|
50MG | 852 | Get Quote |
|
100MG | 1152 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameElacestrant dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionElacestrant (RAD-1901) is a novel, orally bioavailable small-molecule selective estrogen receptor degrader (SERD).
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DescriptionElacestrant (RAD-1901) is a novel, orally bioavailable small-molecule selective estrogen receptor degrader (SERD); inhibits ERα expression in MCF-7 cells (IC50=0.6 nM); induces the degradation of ER, inhibits ER-mediated signaling and growth of ER+ breast cancer cell lines in vitro and in vivo, and significantly inhibits tumor growth of multiple PDX models.Breast Cancer Phase 2 Clinical
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SynonymsRAD-1901 dihydrochloride
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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RecptorEstrogen Receptor/ERR
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Research AreaCancer
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IndicationBreast Cancer
Chemical Information
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CAS Number1349723-93-8
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Formula Weight531.56
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Molecular FormulaC30H40Cl2N2O2
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Purity>98% (HPLC)
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SolubilityDMSO: 17.6 mg/mL
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SMILES——
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Chemical Name2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, hydrochloride (1:2), (6R)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wardell SE, et al. Endocr Relat Cancer. 2015 Oct;22(5):713-24.
2. Garner F, et al. Anticancer Drugs. 2015 Oct;26(9):948-56.
3. Bihani T, et al. Clin Cancer Res. 2017 May 4. pii: clincanres.2561.2016.
2. Garner F, et al. Anticancer Drugs. 2015 Oct;26(9):948-56.
3. Bihani T, et al. Clin Cancer Res. 2017 May 4. pii: clincanres.2561.2016.
molnova catalog
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